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  1. Deutsche Forschungsgemeinschaft (DFG)
  2. Friedrich-Alexander Universität Erlangen-Nürnberg

MISSION

"Interdisciplinary kidney research to advance understanding of disease mechanisms and develop new therapeutic concepts"

TRR374

Contact:
Dr. Markus Bohn
Email
Tel.: ++49 (0)9131 8545857

Publications

  

Bib

Please note that it is mandatory to state the source of funding in publications:
„Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), project number 387509280, SFB 1350“ . 

For publications related to the TRR 374, please specify „Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), project number 509149993, TRR 374“ .

  

2024

Schueler J, Kuenzel J, Thuesing A, Pion E, Behncke RY, Haegerling R, Fuchs D, Kraus A, Buchholz B, Huang B, Merhof D, Werner JM, Schmidt KM, Hackel C, Aung T, Härteis S.
Ultra high frequency ultrasound enables real-time visualization of blood supply from chorioallantoic membrane to human autosomal dominant polycystic kidney tissue.
Sci Rep 14, 10063 (2024). doi.org/10.1038/s41598-024-60783-3
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Ousingsawat J, Centeio R, Reyne N, McCarron A, Cmielewski P, Schreiber R, diStefano G, Römermann D, Seidler U, Donnelley M, Kunzelmann K.
Inhibition of mucus secretion by niclosamide and benzbromarone in airways and intestine.
Sci Rep. 2024 Jan 17;14(1):1464. doi: 10.1038/s41598-024-51397-w. PMID: 38233410; PMCID: PMC10794189.
PubMed

Ousingsawat J, Centeio R, Schreiber R, Kunzelmann K.
Niclosamide, but not ivermectin, inhibits anoctamin 1 and 6 and attenuates inflammation of the respiratory tract.
Pflugers Arch. 2024 Feb;476(2):211-227. doi: 10.1007/s00424-023-02878-w. Epub 2023 Nov 18. PMID: 37979051; PMCID: PMC10791962.
PubMed

Sandersfeld M, Büttner-Herold M, Ferrazzi F, Amann K, Benz K, Daniel C.
Macrophage subpopulations in pediatric patients with lupus nephritis and other inflammatory diseases affecting the kidney.
Arthritis Res Ther. 2024 Feb 8;26(1):46. doi: 10.1186/s13075-024-03281-1. PMID: 38331818; PMCID: PMC10851514.
PubMed

Sure F, Einsiedel J, Gmeiner P, Duchstein P, Zahn D, Korbmacher C, Ilyaskin AV.
The small molecule activator S3969 stimulates the epithelial sodium channel (ENaC) by interacting with a specific binding pocket in the channel's β-subunit.
J Biol Chem. 2024 Feb 22:105785. doi: 10.1016/j.jbc.2024.105785. Epub ahead of print. PMID: 38401845.
PubMed

Angeloni M, van Doeveren T, Lindner S, Volland P, Schmelmer J, Foersch S, Matek C, Stoehr R, Geppert CI, Heers H, Wach S, Taubert H, Sikic D, Wullich B, van Leenders GJ, Zaburdaev V, Eckstein M, Hartmann A, Boormans JL, Ferrazzi F, Bahlinger V.
A deep-learning workflow to predict upper tract urothelial carcinoma protein-based subtypes from H&E slides supporting the prioritization of patients for molecular testing.
J Pathol Clin Res. 2024 Mar;10(2):e12369. doi: 10.1002/2056-4538.12369. PMID: 38504364; PMCID: PMC10951050.
PubMed

Miyauchi H, Geisberger S, Luft FC, Wilck N, Stegbauer J, Wiig H, Dechend R, Jantsch J, Kleinewietfeld M, Kempa S, Müller DN.
Sodium as an Important Regulator of Immunometabolism.
Hypertension. 2024 Mar;81(3):426-435. doi: 10.1161/HYPERTENSIONAHA.123.19489. Epub 2023 Sep 7. PMID: 37675565; PMCID: PMC10863658.
PubMed

Skoczynski K, Kraus A, Daniel C, Büttner-Herold M, Amann K, Schiffer M, Hermann K, Herrnberger-Eimer L, Tamm ER, Buchholz B.
The extracellular matrix protein fibronectin promotes metanephric kidney development.
Pflugers Arch. 2024 Apr 2. doi: 10.1007/s00424-024-02954-9. Epub ahead of print. PMID: 38563997.
PubMed

Kösters P, Cazorla-Vázquez S, Krüger R, Daniel C, Vonbrunn E, Amann K, Engel FB.
Adhesion G Protein-Coupled Receptor Gpr126 (Adgrg6) Expression Profiling in Diseased Mouse, Rat, and Human Kidneys.
Cells. 2024 May 18;13(10):874. doi: 10.3390/cells13100874. PMID: 38786096; PMCID: PMC11119830.
PubMed

Schlieben LD, Carta MG, Moskalev EA, Stöhr R, Metzler M, Besendörfer M, Meidenbauer N, Semrau S, Janka R, Grützmann R, Wiemann S, Hartmann A, Agaimy A, Haller F, Ferrazzi F.
Machine Learning-Supported Diagnosis of Small Blue Round Cell Sarcomas Using Targeted RNA Sequencing.
J Mol Diagn. 2024 May;26(5):387-398. doi: 10.1016/j.jmoldx.2024.02.002. Epub 2024 Feb 21. PMID: 38395409.
PubMed

Schreiber R, Ousingsawat J, Kunzelmann K.
The anoctamins: Structure and function.
Cell Calcium. 2024 Jun;120:102885. doi: 10.1016/j.ceca.2024.102885. Epub 2024 Apr 15. PMID: 38642428.
PubMed

Kunzelmann K, Ousingsawat J, Schreiber R. VSI:
The anoctamins: Structure and function: "Intracellular" anoctamins.
Cell Calcium. 2024 Jun;120:102888. doi: 10.1016/j.ceca.2024.102888. Epub 2024 Apr 17. PMID: 38657371.
PubMed

Ousingsawat J, Talbi K, Gómez-Martín H, Koy A, Fernández-Jaén A, Tekgül H, Serdaroğlu E, Schreiber R, Ortigoza-Escobar JD, Kunzelmann K.
Broadening the clinical spectrum: molecular mechanisms and new phenotypes of ANO3-dystonia.
Brain. 2024 Jun 3;147(6):1982-1995. doi: 10.1093/brain/awad412. PMID: 38079528.
PubMed

Kraus A, Skoczynski K, Brötsch M, Burzlaff N, Leipziger J, Schiffer M, Büttner-Herold M, Buchholz B.
P2Y2R and Cyst Growth in Polycystic Kidney Disease.
J Am Soc Nephrol. 2024 Jun 7. doi: 10.1681/ASN.0000000000000416. Epub ahead of print. PMID: 38848134.
Pubmed

Vonbrunn E, Daniel C.
Die Komplementkaskade in der Nierenpathologie [The complement cascade in renal pathology].
Pathologie (Heidelb). 2024 Jul;45(4):246-253. German. doi: 10.1007/s00292-024-01320-x. Epub 2024 Apr 5. PMID: 38578365.
PubMed

Büttner-Herold M, Amann K, Velden J.
Nephropathologie infektiöser Erkrankungen [Nephropathology of infectious disease].
Pathologie (Heidelb). 2024 Jul;45(4):254-260. German. doi: 10.1007/s00292-024-01322-9. Epub 2024 Apr 10. PMID: 38598098.
PubMed

Wopperer FJ, Olinger E, Wiesener A, Broeker KAE, Knaup KX, Schaefer JT, Galiano M, Schneider K, Schiffer M; Genomics England Research Consortium; Büttner-Herold M, Reis A, Schmieder R, Pasutto F, Hilgers KF, Poglitsch M, Ziegler C, Shoemaker R, Sayer JA, Wiesener MS.
Progressive Kidney Failure by Angiotensinogen Inactivation in the Germline.
Hypertension. 2024 Sep;81(9):1857-1868. doi: 10.1161/HYPERTENSIONAHA.124.22806. Epub 2024 Jul 15. PMID: 39005223.
PubMed

Sure F, Afonso S, Essigke D, Schmidt P, Kalo MZ, Nesterov V, Kißler A, Bertog M, Rinke R, Wittmann S, Broeker KAE, Gramberg T, Artunc F, Korbmacher C, Ilyaskin AV.
Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney.
J Am Soc Nephrol. 2024 Oct 23. doi: 10.1681/ASN.0000000521. Epub ahead of print. PMID: 39441656.
PubMed

Herold JM, Wiegrebe S, Nano J, Jung B, Gorski M, Thorand B, Koenig W, Zeller T, Zimmermann ME, Burkhardt R, Banas B, Küchenhoff H, Stark KJ, Peters A, Böger CA, Heid IM.
Population-based reference values for kidney function and kidney function decline in 25- to 95-year-old Germans without and with diabetes.
Kidney Int. 2024 Oct;106(4):699-711. doi: 10.1016/j.kint.2024.06.024. Epub 2024 Jul 29. PMID: 39084259.
PubMed

Jensen M, Heinl ES, Federlein A, Schwartz U, Lund L, Madsen K, Jensen BL, Schweda F.
Identification of natriuretic peptide receptor A-related gene expression signatures in podocytes in vivo reveals baseline control of protective pathways.
Am J Physiol Renal Physiol. 2024 Nov 1;327(5):F806-F821. doi: 10.1152/ajprenal.00394.2023. Epub 2024 Sep 19. PMID: 39298549.
PubMed

  

  



  1. Deutsche Forschungsgemeinschaft (DFG)
  2. Friedrich-Alexander Universität Erlangen-Nürnberg

MISSION

"Interdisciplinary kidney research to advance understanding of disease mechanisms and develop new therapeutic concepts"

TRR374

Contact:
Dr. Markus Bohn
Email
Tel.: ++49 (0)9131 8545857