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Prof. Dr. Klaus Stark

Lebenslauf

  • 1991-1996 Studium der Biologie (Diplom) an der Universität Regensburg
  • 1996-2002 Wissenschaftlicher Mitarbeiter am Lehrstuhl für Genetik der Universität Regensburg
  • 1999 Promotion zum Dr. rer. nat.
  • 2002-2004 Wissenschaftlicher Mitarbeiter bei NeuroProfile GmbH
  • 2004-2012 Forschungslaborleiter an der Klinik und Poliklinik für Innere Medizin II des Universitätsklinikums Regensburg
  • 2011 Feststellung der Lehrbefähigung durch die Fakultät für Medizin der Universität Regensburg und Erteilung der Lehrbefugnis für das Fachgebiet Experimentelle Medizin
  • Seit 2012 Wissenschaftlicher Mitarbeiter am Lehrstuhl für Genetische Epidemiologie, Institut für Epidemiologie und Präventivmedizin, Universität Regensburg
  • 2020 Ernennung zum außerplanmäßigen Professor

Forschungsschwerpunkte

  • Molekulare und Genetische Epidemiologie
  • Augenstudie der Universität Regensburg (AugUR)
  • Kardiovaskuläre Erkrankungen
  • Metabolische Phänotypen
  • Biomarker

Publikationen

Wopperer FJ, Knaup KX, Stanzick KJ, Schneider K, Jobst-Schwan T, Ekici AB,
Uebe S, Wenzel A, Schliep S, Schürfeld C, Seitz R, Bernhardt W, Gödel M,
Wiesener A, Popp B, Stark KJ, Gröne HJ, Friedrich B, Weiß M, Basic-Jukic N,
Schiffer M, Schröppel B, Huettel B, Beck BB; Genomics England Research
Consortium, Sayer JA, Ziegler C, Büttner-Herold M, Amann K, Heid IM, Reis A,
Pasutto F, Wiesener MS. Diverse molecular causes of unsolved autosomal dominant
tubulointerstitial kidney diseases. Kidney Int. 2022 Aug;102(2):405-420. doi:
10.1016/j.kint.2022.04.031. Epub 2022 May 26. PMID: 35643372.

Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, Sveinbjornsson G,
Winkler TW, Günther F, Stark KJ, Chai JF, Tayo BO, Wuttke M, Li Y, Tin A,
Ahluwalia TS, Ärnlöv J, Åsvold BO, Bakker SJL, Banas B, Bansal N, Biggs ML,
Biino G, Böhnke M, Boerwinkle E, Bottinger EP, Brenner H, Brumpton B, Carroll
RJ, Chaker L, Chalmers J, Chee ML, Chee ML, Cheng CY, Chu AY, Ciullo M, Cocca M,
Cook JP, Coresh J, Cusi D, de Borst MH, Degenhardt F, Eckardt KU, Endlich K,
Evans MK, Feitosa MF, Franke A, Freitag-Wolf S, Fuchsberger C, Gampawar P,
Gansevoort RT, Ghanbari M, Ghasemi S, Giedraitis V, Gieger C, Gudbjartsson DF,
Hallan S, Hamet P, Hishida A, Ho K, Hofer E, Holleczek B, Holm H, Hoppmann A,
Horn K, Hutri-Kähönen N, Hveem K, Hwang SJ, Ikram MA, Josyula NS, Jung B,
Kähönen M, Karabegović I, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B,
Kuusisto J, Laakso M, Lange LA, Lehtimäki T, Li M, Lieb W; Lifelines Cohort
Study, Lind L, Lindgren CM, Loos RJF, Lukas MA, Lyytikäinen LP, Mahajan A,
Matias-Garcia PR, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP,
Mononen N, Morris AP, Mychaleckyj JC, Nadkarni GN, Naito M, Nakatochi M, Nalls
MA, Nauck M, Nikus K, Ning B, Nolte IM, Nutile T, O'Donoghue ML, O'Connell J,
Olafsson I, Orho-Melander M, Parsa A, Pendergrass SA, Penninx BWJH, Pirastu M,
Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rheinberger M, Rice KM, Rizzi F,
Rosenkranz AR, Rossing P, Rotter JI, Ruggiero D, Ryan KA, Sabanayagam C, Salvi
E, Schmidt H, Schmidt R, Scholz M, Schöttker B, Schulz CA, Sedaghat S, Shaffer
CM, Sieber KB, Sim X, Sims M, Snieder H, Stanzick KJ, Thorsteinsdottir U,
Stocker H, Strauch K, Stringham HM, Sulem P, Szymczak S, Taylor KD, Thio CHL,
Tremblay J, Vaccargiu S, van der Harst P, van der Most PJ, Verweij N, Völker U,
Wakai K, Waldenberger M, Wallentin L, Wallner S, Wang J, Waterworth DM, White
HD, Willer CJ, Wong TY, Woodward M, Yang Q, Yerges-Armstrong LM, Zimmermann M,
Zonderman AB, Bergler T, Stefansson K, Böger CA, Pattaro C, Köttgen A,
Kronenberg F, Heid IM. Genetic loci and prioritization of genes for kidney
function decline derived from a meta-analysis of 62 longitudinal genome-wide
association studies. Kidney Int. 2022 Jun 16:S0085-2538(22)00454-9. doi:
10.1016/j.kint.2022.05.021. Epub ahead of print. PMID: 35716955.

Winkler TW, Rasheed H, Teumer A, Gorski M, Rowan BX, Stanzick KJ, Thomas LF,
Tin A, Hoppmann A, Chu AY, Tayo B, Thio CHL, Cusi D, Chai JF, Sieber KB, Horn K,
Li M, Scholz M, Cocca M, Wuttke M, van der Most PJ, Yang Q, Ghasemi S, Nutile T,
Li Y, Pontali G, Günther F, Dehghan A, Correa A, Parsa A, Feresin A, de Vries
APJ, Zonderman AB, Smith AV, Oldehinkel AJ, De Grandi A, Rosenkranz AR, Franke
A, Teren A, Metspalu A, Hicks AA, Morris AP, Tönjes A, Morgan A, Podgornaia AI,
Peters A, Körner A, Mahajan A, Campbell A, Freedman BI, Spedicati B, Ponte B,
Schöttker B, Brumpton B, Banas B, Krämer BK, Jung B, Åsvold BO, Smith BH, Ning
B, Penninx BWJH, Vanderwerff BR, Psaty BM, Kammerer CM, Langefeld CD, Hayward C,
Spracklen CN, Robinson-Cohen C, Hartman CA, Lindgren CM, Wang C, Sabanayagam C,
Heng CK, Lanzani C, Khor CC, Cheng CY, Fuchsberger C, Gieger C, Shaffer CM,
Schulz CA, Willer CJ, Chasman DI, Gudbjartsson DF, Ruggiero D, Toniolo D,
Czamara D, Porteous DJ, Waterworth DM, Mascalzoni D, Mook-Kanamori DO, Reilly
DF, Daw EW, Hofer E, Boerwinkle E, Salvi E, Bottinger EP, Tai ES, Catamo E,
Rizzi F, Guo F, Rivadeneira F, Guilianini F, Sveinbjornsson G, Ehret G, Waeber
G, Biino G, Girotto G, Pistis G, Nadkarni GN, Delgado GE, Montgomery GW, Snieder
H, Campbell H, White HD, Gao H, Stringham HM, Schmidt H, Li H, Brenner H, Holm
H, Kirsten H, Kramer H, Rudan I, Nolte IM, Tzoulaki I, Olafsson I, Martins J,
Cook JP, Wilson JF, Halbritter J, Felix JF, Divers J, Kooner JS, Lee JJ,
O'Connell J, Rotter JI, Liu J, Xu J, Thiery J, Ärnlöv J, Kuusisto J,
Jakobsdottir J, Tremblay J, Chambers JC, Whitfield JB, Gaziano JM, Marten J,
Coresh J, Jonas JB, Mychaleckyj JC, Christensen K, Eckardt KU, Mohlke KL,
Endlich K, Dittrich K, Ryan KA, Rice KM, Taylor KD, Ho K, Nikus K, Matsuda K,
Strauch K, Miliku K, Hveem K, Lind L, Wallentin L, Yerges-Armstrong LM, Raffield
LM, Phillips LS, Launer LJ, Lyytikäinen LP, Lange LA, Citterio L, Klaric L,
Ikram MA, Ising M, Kleber ME, Francescatto M, Concas MP, Ciullo M, Piratsu M,
Orho-Melander M, Laakso M, Loeffler M, Perola M, de Borst MH, Gögele M, Bianca
M, Lukas MA, Feitosa MF, Biggs ML, Wojczynski MK, Kavousi M, Kanai M, Akiyama M,
Yasuda M, Nauck M, Waldenberger M, Chee ML, Chee ML, Boehnke M, Preuss MH,
Stumvoll M, Province MA, Evans MK, O'Donoghue ML, Kubo M, Kähönen M, Kastarinen
M, Nalls MA, Kuokkanen M, Ghanbari M, Bochud M, Josyula NS, Martin NG, Tan NYQ,
Palmer ND, Pirastu N, Schupf N, Verweij N, Hutri-Kähönen N, Mononen N, Bansal N,
Devuyst O, Melander O, Raitakari OT, Polasek O, Manunta P, Gasparini P, Mishra
PP, Sulem P, Magnusson PKE, Elliott P, Ridker PM, Hamet P, Svensson PO, Joshi
PK, Kovacs P, Pramstaller PP, Rossing P, Vollenweider P, van der Harst P,
Dorajoo R, Sim RZH, Burkhardt R, Tao R, Noordam R, Mägi R, Schmidt R, de Mutsert
R, Rueedi R, van Dam RM, Carroll RJ, Gansevoort RT, Loos RJF, Felicita SC,
Sedaghat S, Padmanabhan S, Freitag-Wolf S, Pendergrass SA, Graham SE, Gordon SD,
Hwang SJ, Kerr SM, Vaccargiu S, Patil SB, Hallan S, Bakker SJL, Lim SC, Lucae S,
Vogelezang S, Bergmann S, Corre T, Ahluwalia TS, Lehtimäki T, Boutin TS,
Meitinger T, Wong TY, Bergler T, Rabelink TJ, Esko T, Haller T, Thorsteinsdottir
U, Völker U, Foo VHX, Salomaa V, Vitart V, Giedraitis V, Gudnason V, Jaddoe VWV,
Huang W, Zhang W, Wei WB, Kiess W, März W, Koenig W, Lieb W, Gao X, Sim X, Wang
YX, Friedlander Y, Tham YC, Kamatani Y, Okada Y, Milaneschi Y, Yu Z; Lifelines
cohort study; DiscovEHR/MyCode study; VA Million Veteran Program, Stark KJ,
Stefansson K, Böger CA, Hung AM, Kronenberg F, Köttgen A, Pattaro C, Heid IM.
Differential and shared genetic effects on kidney function between diabetic and
non-diabetic individuals. Commun Biol. 2022 Jun 13;5(1):580. doi:
10.1038/s42003-022-03448-z. PMID: 35697829; PMCID: PMC9192715.

Einhauser S, Peterhoff D, Beileke S, Günther F, Niller HH, Steininger P,
Knöll A, Korn K, Berr M, Schütz A, Wiegrebe S, Stark KJ, Gessner A, Burkhardt R,
Kabesch M, Schedl H, Küchenhoff H, Pfahlberg AB, Heid IM, Gefeller O, Überla K,
Wagner R. Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and
Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County-Results
from a Population-Based Longitudinal Study in Germany. Viruses. 2022 May
27;14(6):1168. doi: 10.3390/v14061168. PMID: 35746640; PMCID: PMC9228731.

Koller A, Brandl C, Lamina C, Zimmermann ME, Summerer M, Stark KJ, Würzner R,
Heid IM, Kronenberg F. Relative Telomere Length Is Associated With Age-Related
Macular Degeneration in Women. Invest Ophthalmol Vis Sci. 2022 May 2;63(5):30.
doi: 10.1167/iovs.63.5.30. PMID: 35612837; PMCID: PMC9150829.

Mauschitz MM, Schmitz MT, Verzijden T, Schmid M, Thee EF, Colijn JM, Delcourt
C, Cougnard-Grégoire A, Merle BMJ, Korobelnik JF, Gopinath B, Mitchell P, Elbaz
H, Schuster AK, Wild PS, Brandl C, Stark KJ, Heid IM, Günther F, Peters A,
Klaver CCW, Finger RP; European Eye Epidemiology (E3) Consortium. Physical
Activity, Incidence, and Progression of Age-Related Macular Degeneration: A
Multicohort Study. Am J Ophthalmol. 2022 Apr;236:99-106. doi:
10.1016/j.ajo.2021.10.008. Epub 2021 Oct 22. PMID: 34695401.

Brandl C, Zimmermann ME, Günther F, Dietl A, Küchenhoff H, Loss J, Stark KJ,
Heid IM. Changes in healthcare seeking and lifestyle in old aged individuals
during COVID-19 lockdown in Germany: the population-based AugUR study. BMC
Geriatr. 2022 Jan 8;22(1):34. doi: 10.1186/s12877-021-02677-x. PMID: 34998375;
PMCID: PMC8742665.

Matos C, Peter K, Weich L, Peuker A, Schoenhammer G, Roider T, Ghimire S,
Babl N, Decking S, Güllstorf M, Kröger N, Hammon K, Herr W, Stark K, Heid IM,
Renner K, Holler E, Kreutz M. Anti-Thymocyte Globulin Treatment Augments
1,25-Dihydroxyvitamin D3 Serum Levels in Patients Undergoing Hematopoietic Stem
Cell Transplantation. Front Immunol. 2022 Jan 4;12:803726. doi:
10.3389/fimmu.2021.803726. PMID: 35058935; PMCID: PMC8763972.

Brandl C, Günther F, Zimmermann ME, Hartmann KI, Eberlein G, Barth T, Winkler
TW, Linkohr B, Heier M, Peters A, Li JQ, Finger RP, Helbig H, Weber BHF,
Küchenhoff H, Mueller A, Stark KJ, Heid IM. Incidence, progression and risk
factors of age-related macular degeneration in 35-95-year-old individuals from
three jointly designed German cohort studies. BMJ Open Ophthalmol. 2022 Jan
4;7(1):e000912. doi: 10.1136/bmjophth-2021-000912. PMID: 35047672; PMCID:
PMC8728420.

Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I,
Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita
A, Choudhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui
Q, Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H,
Olafsson I, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed
H, Ruotsalainen SE, Havulinna AS, Veturi Y, Feng Q, Rosenthal EA, Lingren T,
Pacheco JA, Pendergrass SA, Haessler J, Giulianini F, Bradford Y, Miller JE,
Campbell A, Lin K, Millwood IY, Hindy G, Rasheed A, Faul JD, Zhao W, Weir DR,
Turman C, Huang H, Graff M, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM,
Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K,
Medina-Gomez C, Pitsillides A, Hottenga JJ, Willemsen G, Wood AR, Ji Y, Gao Z,
Haworth S, Mitchell RE, Chai JF, Aadahl M, Yao J, Manichaikul A, Warren HR,
Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Sidore
C, Fiorillo E, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N,
Møllehave LT, Thuesen BH, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A,
Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Daw EW, Zmuda JM,
Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Feitosa MF, Wojczynski MK,
Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Kember
RL, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Huo S, Ikeda DD,
Iha H, Yang J, Liu J, Leonard HL, Marten J, Schmidt B, Arendt M, Smyth LJ,
Cañadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kähönen N, Sim X, Xia R,
Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Ahmed M, Jackson AU, Irvin MR,
Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Chai
X, Prasad G, Lorés-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F,
Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T,
Ruggiero D, Sung YJ, Hung YJ, Chen S, Liu F, Yang J, Kentistou KA, Gorski M,
Brumat M, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M,
Xue C, Zhang J, Concas MP, Vaccargiu S, van der Most PJ, Pitkänen N, Cade BE,
Lee J, van der Laan SW, Chitrala KN, Weiss S, Zimmermann ME, Lee JY, Choi HS,
Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS,
Couture C, Lyytikäinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hildalgo
B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Schwander K, Terzikhan
N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Highland HM, Young
KL, Kawaguchi T, Thiery J, Bis JC, Nadkarni GN, Launer LJ, Li H, Nalls MA,
Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jäger S, Nabika T, Al-
Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T,
Bhatti KF, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X,
Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O,
Hansen T, Mitchell P, Hewitt AW, Kähönen M, Pérusse L, Bouchard C, Tönjes A,
Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellström D, Cho YS,
Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Völzke H, Homuth G,
Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala
K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Chen YE, Bandinelli
S, Dedoussis G, Thanaraj TA, Kardia SLR, Kato N, Schulze MB, Girotto G, Jung B,
Böger CA, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield
MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P,
Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng
W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson
AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC,
Arnett DK, Walker M, Koistinen HA, Chandak GR, Yajnik CS, Mercader JM, Tusié-
Luna T, Aguilar-Salinas CA, Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam
RM, Lehtimäki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F,
Jöckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn
CM, Lu F, Qu J, Hishigaki H, Lin X, März W, Parra EJ, Cruz M, Gudnason V, Tardif
JC, Lettre G, 't Hart LM, Elders PJM, Damrauer SM, Kumari M, Kivimaki M, van der
Harst P, Spector TD, Loos RJF, Province MA, Psaty BM, Brandslund I, Pramstaller
PP, Christensen K, Ripatti S, Widén E, Hakonarson H, Grant SFA, Kiemeney LALM,
de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW,
Linneberg A, Jukema JW, Khera AV, Männikkö M, Jarvelin MR, Kutalik Z, Cucca F,
Mook-Kanamori DO, van Dijk KW, Watkins H, Strachan DP, Grarup N, Sever P,
Poulter N, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY,
Wong TY, Khor CC, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL,
Magnusson PKE, Boomsma DI, de Geus EJC, Cupples LA, van Meurs JBJ, Ghanbari M,
Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E,
Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries
PS, Morrison AC, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas
S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Justice AE, Baras A,
Buring JE, Ridker PM, Chasman DI, Kooperberg C, Wei WQ, Jarvik GP, Namjou B,
Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, Åsvold BO, Kubo M,
Kamatani Y, Okada Y, Murakami Y, Thorsteinsdottir U, Stefansson K, Ho YL, Lynch
JA, Rader DJ, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson P,
Rotimi CN, Hazelhurst S, Ramsay M, Trembath RC, van Heel DA, Tamiya G, Yamamoto
M, Kim BJ, Mohlke KL, Frayling TM, Hirschhorn JN, Kathiresan S; VA Million
Veteran Program; Global Lipids Genetics Consortium*, Boehnke M, Natarajan P,
Peloso GM, Brown CD, Morris AP, Assimes TL, Deloukas P, Sun YV, Willer CJ. The
power of genetic diversity in genome-wide association studies of lipids. Nature.
2021 Dec;600(7890):675-679. doi: 10.1038/s41586-021-04064-3. Epub 2021 Dec 9.
PMID: 34887591; PMCID: PMC8730582.

Dietl A, Zimmermann ME, Brandl C, Wallner S, Burkhardt R, Maier LS, Luchner
A, Heid IM, Stark KJ. Distribution and specificity of high-sensitivity cardiac
troponin T in older adults without acute cardiac conditions: cross-sectional
results from the population-based AugUR study. BMJ Open. 2021 Nov
2;11(11):e052004. doi: 10.1136/bmjopen-2021-052004. PMID: 34728452; PMCID:
PMC8565570.

Drewitz KP, Stark KJ, Zimmermann ME, Heid IM, Apfelbacher CJ. Frequency of
hand eczema in the elderly: Cross-sectional findings from the German AugUR
study. Contact Dermatitis. 2021 Nov;85(5):489-493. doi: 10.1111/cod.13920. Epub
2021 Jul 12. PMID: 34161620.

Stanzick KJ, Li Y, Schlosser P, Gorski M, Wuttke M, Thomas LF, Rasheed H,
Rowan BX, Graham SE, Vanderweff BR, Patil SB; VA Million Veteran Program,
Robinson-Cohen C, Gaziano JM, O'Donnell CJ, Willer CJ, Hallan S, Åsvold BO,
Gessner A, Hung AM, Pattaro C, Köttgen A, Stark KJ, Heid IM, Winkler TW.
Discovery and prioritization of variants and genes for kidney function in >1.2
million individuals. Nat Commun. 2021 Jul 16;12(1):4350. doi:
10.1038/s41467-021-24491-0. PMID: 34272381; PMCID: PMC8285412.

Wagner R, Peterhoff D, Beileke S, Günther F, Berr M, Einhauser S, Schütz A,
Niller HH, Steininger P, Knöll A, Tenbusch M, Maier C, Korn K, Stark KJ, Gessner
A, Burkhardt R, Kabesch M, Schedl H, Küchenhoff H, Pfahlberg AB, Heid IM,
Gefeller O, Überla K. Estimates and Determinants of SARS-Cov-2 Seroprevalence
and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based
Tirschenreuth Study in the Hardest-Hit German County in Spring 2020. Viruses.
2021 Jun 10;13(6):1118. doi: 10.3390/v13061118. PMID: 34200766; PMCID:
PMC8230374.

Garnier S, Harakalova M, Weiss S, Mokry M, Regitz-Zagrosek V, Hengstenberg
C, Cappola TP, Isnard R, Arbustini E, Cook SA, van Setten J, Calis JJA,
Hakonarson H, Morley MP, Stark K, Prasad SK, Li J, O'Regan DP, Grasso M, Müller-
Nurasyid M, Meitinger T, Empana JP, Strauch K, Waldenberger M, Marguiles KB,
Seidman CE, Kararigas G, Meder B, Haas J, Boutouyrie P, Lacolley P, Jouven X,
Erdmann J, Blankenberg S, Wichter T, Ruppert V, Tavazzi L, Dubourg O, Roizes G,
Dorent R, de Groote P, Fauchier L, Trochu JN, Aupetit JF, Bilinska ZT, Germain
M, Völker U, Hemerich D, Raji I, Bacq-Daian D, Proust C, Remior P, Gomez-Bueno
M, Lehnert K, Maas R, Olaso R, Saripella GV, Felix SB, McGinn S, Duboscq-Bidot
L, van Mil A, Besse C, Fontaine V, Blanché H, Ader F, Keating B, Curjol A,
Boland A, Komajda M, Cambien F, Deleuze JF, Dörr M, Asselbergs FW, Villard E,
Trégouët DA, Charron P. Genome-wide association analysis in dilated
cardiomyopathy reveals two new players in systolic heart failure on chromosomes
3p25.1 and 22q11.23. Eur Heart J. 2021 May 21;42(20):2000-2011. doi:
10.1093/eurheartj/ehab030. Erratum in: Eur Heart J. 2021 May 21;42(20):2011.
PMID: 33677556; PMCID: PMC8139853.

Peter K, Siska PJ, Roider T, Matos C, Bruns H, Renner K, Singer K, Weber D,
Güllstorf M, Kröger N, Wolff D, Herr W, Ayuk F, Holler E, Stark K, Heid IM,
Kreutz M. 1,25-dihydroxyvitamin-D3 but not the clinically applied marker
25-hydroxyvitamin-D3 predicts survival after stem cell transplantation. Bone
Marrow Transplant. 2021 Feb;56(2):419-433. doi: 10.1038/s41409-020-01031-w. Epub
2020 Aug 27. PMID: 32855442; PMCID: PMC7870805.

Guenther F, Brandl C, Winkler TW, Wanner V, Stark K, Kuechenhoff H, Heid IM.
Chances and challenges of machine learning-based disease classification in
genetic association studies illustrated on age-related macular degeneration.
Genet Epidemiol. 2020 Oct;44(7):759-777. doi: 10.1002/gepi.22336. Epub 2020 Aug
2. PMID: 32741009.

Winkler TW, Grassmann F, Brandl C, Kiel C, Günther F, Strunz T, Weidner L,
Zimmermann ME, Korb CA, Poplawski A, Schuster AK, Müller-Nurasyid M, Peters A,
Rauscher FG, Elze T, Horn K, Scholz M, Cañadas-Garre M, McKnight AJ, Quinn N,
Hogg RE, Küchenhoff H, Heid IM, Stark KJ, Weber BHF. Genome-wide association
meta-analysis for early age-related macular degeneration highlights novel loci
and insights for advanced disease. BMC Med Genomics. 2020 Aug 26;13(1):120. doi:
10.1186/s12920-020-00760-7. PMID: 32843070; PMCID: PMC7449002.

Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M,
Empana JP, Morley MP, Perret C, Stark K, Bick AG, Prasad SK, Kriebel J, Li J,
Tiret L, Strauch K, O'Regan DP, Marguiles KB, Seidman JG, Boutouyrie P, Lacolley
P, Jouven X, Hengstenberg C, Komajda M, Hakonarson H, Isnard R, Arbustini E,
Grallert H, Cook SA, Seidman CE, Regitz-Zagrosek V, Cappola TP, Charron P,
Cambien F, Villard E. Correction: Exome-wide association study reveals novel
susceptibility genes to sporadic dilated cardiomyopathy. PLoS One. 2020 Feb
14;15(2):e0229472. doi: 10.1371/journal.pone.0229472. Erratum for: PLoS One.
2017 Mar 15;12(3):e0172995. PMID: 32059048; PMCID: PMC7021299.

Teumer A, Trenkwalder T, Kessler T, Jamshidi Y, van den Berg ME, Kaess B,
Nelson CP, Bastiaenen R, De Bortoli M, Rossini A, Deisenhofer I, Stark K, Assa
S, Braund PS, Cabrera C, Dominiczak AF, Gögele M, Hall LM, Ikram MA, Kavousi M,
Lackner KJ; Lifelines Cohort Study, Müller C, Münzel T, Nauck M, Padmanabhan S,
Pfeiffer N, Spector TD, Uitterlinden AG, Verweij N, Völker U, Warren HR, Zafar
M, Felix SB, Kors JA, Snieder H, Munroe PB, Pattaro C, Fuchsberger C, Schmidt G,
Nolte IM, Schunkert H, Pramstaller PP, Wild PS, van der Harst P, Stricker BH,
Schnabel RB, Samani NJ, Hengstenberg C, Dörr M, Behr ER, Reinhard W. KCND3
potassium channel gene variant confers susceptibility to electrocardiographic
early repolarization pattern. JCI Insight. 2019 Dec 5;4(23):e131156. doi:
10.1172/jci.insight.131156. PMID: 31600170; PMCID: PMC6962032.

Brandl C, Brücklmayer C, Günther F, Zimmermann ME, Küchenhoff H, Helbig H,
Weber BHF, Heid IM, Stark KJ. Retinal Layer Thicknesses in Early Age-Related
Macular Degeneration: Results From the German AugUR Study. Invest Ophthalmol Vis
Sci. 2019 Apr 1;60(5):1581-1594. doi: 10.1167/iovs.18-25332. PMID: 30995315;
PMCID: PMC6892378.

Rheinberger M, Jung B, Segiet T, Nusser J, Kreisel G, Andreae A, Manz J,
Haas G, Banas B, Stark K, Lammert A, Gorski M, Heid IM, Krämer BK, Böger CA.
Poor risk factor control in outpatients with diabetes mellitus type 2 in
Germany: The DIAbetes COhoRtE (DIACORE) study. PLoS One. 2019 Mar
21;14(3):e0213157. doi: 10.1371/journal.pone.0213157. PMID: 30897159; PMCID:
PMC6428304.

Brandl C, Zimmermann ME, Günther F, Barth T, Olden M, Schelter SC,
Kronenberg F, Loss J, Küchenhoff H, Helbig H, Weber BHF, Stark KJ, Heid IM. On
the impact of different approaches to classify age-related macular degeneration:
Results from the German AugUR study. Sci Rep. 2018 Jun 6;8(1):8675. doi:
10.1038/s41598-018-26629-5. PMID: 29875478; PMCID: PMC5989235.

Winkler TW, Brandl C, Grassmann F, Gorski M, Stark K, Loss J, Weber BHF,
Heid IM; International Age-related Macular Degeneration Genomics Consortium
(IAMDGC). Investigating the modulation of genetic effects on late AMD by age and
sex: Lessons learned and two additional loci. PLoS One. 2018 Mar
12;13(3):e0194321. doi: 10.1371/journal.pone.0194321. PMID: 29529059; PMCID:
PMC5846797.

Grassmann F, Kiel C, Zimmermann ME, Gorski M, Grassmann V, Stark K;
International AMD Genomics Consortium (IAMDGC), Heid IM, Weber BH. Genetic
pleiotropy between age-related macular degeneration and 16 complex diseases and
traits. Genome Med. 2017 Mar 27;9(1):29. doi: 10.1186/s13073-017-0418-0. PMID:
28347358; PMCID: PMC5368911.

Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M,
Empana JP, Morley MP, Perret C, Stark K, Bick AG, Prasad SK, Kriebel J, Li J,
Tiret L, Strauch K, O'Regan DP, Marguiles KB, Seidman JG, Boutouyrie P, Lacolley
P, Jouven X, Hengstenberg C, Komajda M, Hakonarson H, Isnard R, Arbustini E,
Grallert H, Cook SA, Seidman CE, Regitz-Zagrosek V, Cappola TP, Charron P,
Cambien F, Villard E. Exome-wide association study reveals novel susceptibility
genes to sporadic dilated cardiomyopathy. PLoS One. 2017 Mar 15;12(3):e0172995.
doi: 10.1371/journal.pone.0172995. Erratum in: PLoS One. 2020 Feb
14;15(2):e0229472. PMID: 28296976; PMCID: PMC5351854.

Brandl C, Breinlich V, Stark KJ, Enzinger S, Aßenmacher M, Olden M,
Grassmann F, Graw J, Heier M, Peters A, Helbig H, Küchenhoff H, Weber BH, Heid
IM. Features of Age-Related Macular Degeneration in the General Adults and Their
Dependency on Age, Sex, and Smoking: Results from the German KORA Study. PLoS
One. 2016 Nov 28;11(11):e0167181. doi: 10.1371/journal.pone.0167181. PMID:
27893849; PMCID: PMC5125704.

Dietl A, Stark K, Zimmermann ME, Meisinger C, Schunkert H, Birner C, Maier
LS, Peters A, Heid IM, Luchner A. NT-proBNP Predicts Cardiovascular Death in the
General Population Independent of Left Ventricular Mass and Function: Insights
from a Large Population-Based Study with Long-Term Follow-Up. PLoS One. 2016 Oct
6;11(10):e0164060. doi: 10.1371/journal.pone.0164060. PMID: 27711172; PMCID:
PMC5053441.

Olden M, Holle R, Heid IM, Stark K. IDGenerator: unique identifier generator
for epidemiologic or clinical studies. BMC Med Res Methodol. 2016 Sep 15;16:120.
doi: 10.1186/s12874-016-0222-3. PMID: 27628043; PMCID: PMC5024489.

Brandl C, Stark KJ, Wintergerst M, Heinemann M, Heid IM, Finger RP.
Epidemiologie der altersbedingten Makuladegeneration [Epidemiology of age-
related macular degeneration]. Ophthalmologe. 2016 Sep;113(9):735-45. German.
doi: 10.1007/s00347-016-0341-6. PMID: 27541733.

Fritsche LG, Igl W, Bailey JN, Grassmann F, Sengupta S, Bragg-Gresham JL,
Burdon KP, Hebbring SJ, Wen C, Gorski M, Kim IK, Cho D, Zack D, Souied E, Scholl
HP, Bala E, Lee KE, Hunter DJ, Sardell RJ, Mitchell P, Merriam JE, Cipriani V,
Hoffman JD, Schick T, Lechanteur YT, Guymer RH, Johnson MP, Jiang Y, Stanton CM,
Buitendijk GH, Zhan X, Kwong AM, Boleda A, Brooks M, Gieser L, Ratnapriya R,
Branham KE, Foerster JR, Heckenlively JR, Othman MI, Vote BJ, Liang HH, Souzeau
E, McAllister IL, Isaacs T, Hall J, Lake S, Mackey DA, Constable IJ, Craig JE,
Kitchner TE, Yang Z, Su Z, Luo H, Chen D, Ouyang H, Flagg K, Lin D, Mao G,
Ferreyra H, Stark K, von Strachwitz CN, Wolf A, Brandl C, Rudolph G, Olden M,
Morrison MA, Morgan DJ, Schu M, Ahn J, Silvestri G, Tsironi EE, Park KH, Farrer
LA, Orlin A, Brucker A, Li M, Curcio CA, Mohand-Saïd S, Sahel JA, Audo I,
Benchaboune M, Cree AJ, Rennie CA, Goverdhan SV, Grunin M, Hagbi-Levi S,
Campochiaro P, Katsanis N, Holz FG, Blond F, Blanché H, Deleuze JF, Igo RP Jr,
Truitt B, Peachey NS, Meuer SM, Myers CE, Moore EL, Klein R, Hauser MA, Postel
EA, Courtenay MD, Schwartz SG, Kovach JL, Scott WK, Liew G, Tan AG, Gopinath B,
Merriam JC, Smith RT, Khan JC, Shahid H, Moore AT, McGrath JA, Laux R, Brantley
MA Jr, Agarwal A, Ersoy L, Caramoy A, Langmann T, Saksens NT, de Jong EK, Hoyng
CB, Cain MS, Richardson AJ, Martin TM, Blangero J, Weeks DE, Dhillon B, van
Duijn CM, Doheny KF, Romm J, Klaver CC, Hayward C, Gorin MB, Klein ML, Baird PN,
den Hollander AI, Fauser S, Yates JR, Allikmets R, Wang JJ, Schaumberg DA, Klein
BE, Hagstrom SA, Chowers I, Lotery AJ, Léveillard T, Zhang K, Brilliant MH,
Hewitt AW, Swaroop A, Chew EY, Pericak-Vance MA, DeAngelis M, Stambolian D,
Haines JL, Iyengar SK, Weber BH, Abecasis GR, Heid IM. A large genome-wide
association study of age-related macular degeneration highlights contributions
of rare and common variants. Nat Genet. 2016 Feb;48(2):134-43. doi:
10.1038/ng.3448. Epub 2015 Dec 21. PMID: 26691988; PMCID: PMC4745342.

Stark K, Olden M, Brandl C, Dietl A, Zimmermann ME, Schelter SC, Loss J,
Leitzmann MF, Böger CA, Luchner A, Kronenberg F, Helbig H, Weber BH, Heid IM.
The German AugUR study: study protocol of a prospective study to investigate
chronic diseases in the elderly. BMC Geriatr. 2015 Oct 21;15:130. doi:
10.1186/s12877-015-0122-0. PMID: 26489512; PMCID: PMC4617905.

Fuerstenau-Sharp M, Zimmermann ME, Stark K, Jentsch N, Klingenstein M,
Drzymalski M, Wagner S, Maier LS, Hehr U, Baessler A, Fischer M, Hengstenberg C.
Generation of highly purified human cardiomyocytes from peripheral blood
mononuclear cell-derived induced pluripotent stem cells. PLoS One. 2015 May
13;10(5):e0126596. doi: 10.1371/journal.pone.0126596. PMID: 25970162; PMCID:
PMC4430251.

Stark K, Straub RH, Rovenský J, Blažičková S, Eiselt G, Schmidt M. CYB5A
polymorphism increases androgens and reduces risk of rheumatoid arthritis in
women. Arthritis Res Ther. 2015 Mar 11;17(1):56. doi: 10.1186/s13075-015-0574-9.
PMID: 25890314; PMCID: PMC4372052.

Gorski M, Winkler TW, Stark K, Müller-Nurasyid M, Ried JS, Grallert H, Weber
BH, Heid IM. Harmonization of study and reference data by PhaseLift: saving time
when imputing study data. Genet Epidemiol. 2014 Jul;38(5):381-8. doi:
10.1002/gepi.21812. PMID: 24962562.

Ruedel A, Stark K, Kaufmann S, Bauer R, Reinders J, Rovensky J, Blazicková
S, Oefner PJ, Bosserhoff AK. N-cadherin promoter polymorphisms and risk of
osteoarthritis. FASEB J. 2014 Feb;28(2):683-91. doi: 10.1096/fj.13-238295. Epub
2013 Oct 22. PMID: 24148886.

Erdmann J, Stark K, Esslinger UB, Rumpf PM, Koesling D, de Wit C, Kaiser FJ,
Braunholz D, Medack A, Fischer M, Zimmermann ME, Tennstedt S, Graf E, Eck S,
Aherrahrou Z, Nahrstaedt J, Willenborg C, Bruse P, Brænne I, Nöthen MM, Hofmann
P, Braund PS, Mergia E, Reinhard W, Burgdorf C, Schreiber S, Balmforth AJ, Hall
AS, Bertram L, Steinhagen-Thiessen E, Li SC, März W, Reilly M, Kathiresan S,
McPherson R, Walter U; CARDIoGRAM, Ott J, Samani NJ, Strom TM, Meitinger T,
Hengstenberg C, Schunkert H. Dysfunctional nitric oxide signalling increases
risk of myocardial infarction. Nature. 2013 Dec 19;504(7480):432-6. doi:
10.1038/nature12722. Epub 2013 Nov 10. PMID: 24213632.

Luchner A, Behrens G, Stritzke J, Markus M, Stark K, Peters A, Meisinger C,
Leitzmann M, Hense HW, Schunkert H, Heid IM. Long-term pattern of brain
natriuretic peptide and N-terminal pro brain natriuretic peptide and its
determinants in the general population: contribution of age, gender, and cardiac
and extra-cardiac factors. Eur J Heart Fail. 2013 Aug;15(8):859-67. doi:
10.1093/eurjhf/hft048. Epub 2013 Apr 7. PMID: 23568644.

Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE,
Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D,
Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR,
Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G,
Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N,
Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson Å, Johnson T,
Kanoni S, Kleber ME, König IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C,
Li G, Mangino M, McArdle WL, Medina-Gomez C, Müller-Nurasyid M, Ngwa JS, Nolte
IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J,
Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van
Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW,
Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL,
Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS,
Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S,
Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrières J, Franke L, Frau F,
Gejman PV, Grallert H, Grönberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL,
Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE,
Hyppönen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, Kähönen M, Kathiresan S,
Kee F, Khaw KT, Kivimäki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto
J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindström J, Liu J,
Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D,
März W, Mateo Leach I, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery
GW, Mooser V, Mühleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G,
Nohr EA, Ong KK, Oostra BA, Palmer CN, Palotie A, Peden JF, Pedersen N, Peters
A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, Pütter C, Radhakrishnan A,
Raitakari O, Rendon A, Rivadeneira F, Rudan I, Saaristo TE, Sambrook JG, Sanders
AR, Sanna S, Saramies J, Schipf S, Schreiber S, Schunkert H, Shin SY, Signorini
S, Sinisalo J, Skrobek B, Soranzo N, Stančáková A, Stark K, Stephens JC,
Stirrups K, Stolk RP, Stumvoll M, Swift AJ, Theodoraki EV, Thorand B, Tregouet
DA, Tremoli E, Van der Klauw MM, van Meurs JB, Vermeulen SH, Viikari J, Virtamo
J, Vitart V, Waeber G, Wang Z, Widén E, Wild SH, Willemsen G, Winkelmann BR,
Witteman JC, Wolffenbuttel BH, Wong A, Wright AF, Zillikens MC, Amouyel P, Boehm
BO, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Cupples LA, Cusi D,
Dedoussis GV, Erdmann J, Eriksson JG, Franks PW, Froguel P, Gieger C, Gyllensten
U, Hamsten A, Harris TB, Hengstenberg C, Hicks AA, Hingorani A, Hinney A, Hofman
A, Hovingh KG, Hveem K, Illig T, Jarvelin MR, Jöckel KH, Keinanen-Kiukaanniemi
SM, Kiemeney LA, Kuh D, Laakso M, Lehtimäki T, Levinson DF, Martin NG, Metspalu
A, Morris AD, Nieminen MS, Njølstad I, Ohlsson C, Oldehinkel AJ, Ouwehand WH,
Palmer LJ, Penninx B, Power C, Province MA, Psaty BM, Qi L, Rauramaa R, Ridker
PM, Ripatti S, Salomaa V, Samani NJ, Snieder H, Sørensen TI, Spector TD,
Stefansson K, Tönjes A, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst
P, Vollenweider P, Wallaschofski H, Wareham NJ, Watkins H, Wichmann HE, Wilson
JF, Abecasis GR, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox
CS, Frayling T, Groop LC, Haritunian T, Heid IM, Hunter D, Kaplan RC, Karpe F,
Moffatt MF, Mohlke KL, O'Connell JR, Pawitan Y, Schadt EE, Schlessinger D,
Steinthorsdottir V, Strachan DP, Thorsteinsdottir U, van Duijn CM, Visscher PM,
Di Blasio AM, Hirschhorn JN, Lindgren CM, Morris AP, Meyre D, Scherag A,
McCarthy MI, Speliotes EK, North KE, Loos RJ, Ingelsson E. Genome-wide meta-
analysis identifies 11 new loci for anthropometric traits and provides insights
into genetic architecture. Nat Genet. 2013 May;45(5):501-12. doi:
10.1038/ng.2606. Epub 2013 Apr 7. PMID: 23563607; PMCID: PMC3973018.

Zollbrecht C, Grassl M, Fenk S, Höcherl R, Hubauer U, Reinhard W, Esslinger
UB, Ebert S, Langmann T, Stark K, Hengstenberg C. Expression pattern in human
macrophages dependent on 9p21.3 coronary artery disease risk locus.
Atherosclerosis. 2013 Apr;227(2):244-9. doi:
10.1016/j.atherosclerosis.2012.12.030. Epub 2013 Jan 17. PMID: 23375685.

Raffler J, Römisch-Margl W, Petersen AK, Pagel P, Blöchl F, Hengstenberg C,
Illig T, Meisinger C, Stark K, Wichmann HE, Adamski J, Gieger C, Kastenmüller G,
Suhre K. Identification and MS-assisted interpretation of genetically influenced
NMR signals in human plasma. Genome Med. 2013 Feb 15;5(2):13. doi:
10.1186/gm417. PMID: 23414815; PMCID: PMC3706909.

CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M,
Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA,
Stirrups K, König IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ,
Chambers JC, Esko T, Folkersen L, Goel A, Grundberg E, Havulinna AS, Ho WK,
Hopewell JC, Eriksson N, Kleber ME, Kristiansson K, Lundmark P, Lyytikäinen LP,
Rafelt S, Shungin D, Strawbridge RJ, Thorleifsson G, Tikkanen E, Van Zuydam N,
Voight BF, Waite LL, Zhang W, Ziegler A, Absher D, Altshuler D, Balmforth AJ,
Barroso I, Braund PS, Burgdorf C, Claudi-Boehm S, Cox D, Dimitriou M, Do R;
DIAGRAM Consortium; CARDIOGENICS Consortium, Doney AS, El Mokhtari N, Eriksson
P, Fischer K, Fontanillas P, Franco-Cereceda A, Gigante B, Groop L, Gustafsson
S, Hager J, Hallmans G, Han BG, Hunt SE, Kang HM, Illig T, Kessler T, Knowles
JW, Kolovou G, Kuusisto J, Langenberg C, Langford C, Leander K, Lokki ML,
Lundmark A, McCarthy MI, Meisinger C, Melander O, Mihailov E, Maouche S, Morris
AD, Müller-Nurasyid M; MuTHER Consortium, Nikus K, Peden JF, Rayner NW, Rasheed
A, Rosinger S, Rubin D, Rumpf MP, Schäfer A, Sivananthan M, Song C, Stewart AF,
Tan ST, Thorgeirsson G, van der Schoot CE, Wagner PJ; Wellcome Trust Case
Control Consortium, Wells GA, Wild PS, Yang TP, Amouyel P, Arveiler D, Basart H,
Boehnke M, Boerwinkle E, Brambilla P, Cambien F, Cupples AL, de Faire U, Dehghan
A, Diemert P, Epstein SE, Evans A, Ferrario MM, Ferrières J, Gauguier D, Go AS,
Goodall AH, Gudnason V, Hazen SL, Holm H, Iribarren C, Jang Y, Kähönen M, Kee F,
Kim HS, Klopp N, Koenig W, Kratzer W, Kuulasmaa K, Laakso M, Laaksonen R, Lee
JY, Lind L, Ouwehand WH, Parish S, Park JE, Pedersen NL, Peters A, Quertermous
T, Rader DJ, Salomaa V, Schadt E, Shah SH, Sinisalo J, Stark K, Stefansson K,
Trégouët DA, Virtamo J, Wallentin L, Wareham N, Zimmermann ME, Nieminen MS,
Hengstenberg C, Sandhu MS, Pastinen T, Syvänen AC, Hovingh GK, Dedoussis G,
Franks PW, Lehtimäki T, Metspalu A, Zalloua PA, Siegbahn A, Schreiber S, Ripatti
S, Blankenberg SS, Perola M, Clarke R, Boehm BO, O'Donnell C, Reilly MP, März W,
Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J,
Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ. Large-scale association
analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013
Jan;45(1):25-33. doi: 10.1038/ng.2480. Epub 2012 Dec 2. PMID: 23202125; PMCID:
PMC3679547.

Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM,
Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong
LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR,
Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J,
Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z,
Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N,
Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J,
Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J,
Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O,
Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA,
Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild
SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L,
Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW,
Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright
AF, Rudan I, Groop LC, Metspalu A, Khaw KT, van Duijn CM, Borecki IB, Province
MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M,
Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K,
Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP,
Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx
B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H,
Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens
MC, Kiemeney LA, Vermeulen SH, Abecasis GR, Schlessinger D, Schipf S, Stumvoll
M, Tönjes A, Spector TD, North KE, Lettre G, McCarthy MI, Berndt SI, Heath AC,
Madden PA, Nyholt DR, Montgomery GW, Martin NG, McKnight B, Strachan DP, Hill
WG, Snieder H, Ridker PM, Thorsteinsdottir U, Stefansson K, Frayling TM,
Hirschhorn JN, Goddard ME, Visscher PM. FTO genotype is associated with
phenotypic variability of body mass index. Nature. 2012 Oct 11;490(7419):267-72.
doi: 10.1038/nature11401. Epub 2012 Sep 16. PMID: 22982992; PMCID: PMC3564953.

Birner C, Dietl A, Deutzmann R, Schröder J, Schmid P, Jungbauer C, Resch M,
Endemann D, Stark K, Riegger G, Luchner A. Proteomic profiling implies
mitochondrial dysfunction in tachycardia-induced heart failure. J Card Fail.
2012 Aug;18(8):660-73. doi: 10.1016/j.cardfail.2012.06.418. PMID: 22858083.

Petersen AK, Stark K, Musameh MD, Nelson CP, Römisch-Margl W, Kremer W,
Raffler J, Krug S, Skurk T, Rist MJ, Daniel H, Hauner H, Adamski J, Tomaszewski
M, Döring A, Peters A, Wichmann HE, Kaess BM, Kalbitzer HR, Huber F, Pfahlert V,
Samani NJ, Kronenberg F, Dieplinger H, Illig T, Hengstenberg C, Suhre K, Gieger
C, Kastenmüller G. Genetic associations with lipoprotein subfractions provide
information on their biological nature. Hum Mol Genet. 2012 Mar
15;21(6):1433-43. doi: 10.1093/hmg/ddr580. Epub 2011 Dec 8. PMID: 22156577.

Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A,
Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde
S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME,
Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager
HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM,
Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson
JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P,
Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS,
Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J,
Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis
JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR,
Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ,
Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A,
Blankenberg S. A genome-wide association study identifies LIPA as a
susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug
1;4(4):403-12. doi: 10.1161/CIRCGENETICS.110.958728. Epub 2011 May 23. PMID:
21606135; PMCID: PMC3157552.

Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberg C, Ruppert
V, Arbustini E, Wichter T, Germain M, Dubourg O, Tavazzi L, Aumont MC, DeGroote
P, Fauchier L, Trochu JN, Gibelin P, Aupetit JF, Stark K, Erdmann J, Hetzer R,
Roberts AM, Barton PJ, Regitz-Zagrosek V; Cardiogenics Consortium, Aslam U,
Duboscq-Bidot L, Meyborg M, Maisch B, Madeira H, Waldenström A, Galve E, Cleland
JG, Dorent R, Roizes G, Zeller T, Blankenberg S, Goodall AH, Cook S, Tregouet
DA, Tiret L, Isnard R, Komajda M, Charron P, Cambien F. A genome-wide
association study identifies two loci associated with heart failure due to
dilated cardiomyopathy. Eur Heart J. 2011 May;32(9):1065-76. doi:
10.1093/eurheartj/ehr105. Epub 2011 Apr 1. PMID: 21459883; PMCID: PMC3086901.

Reinhard W, Kaess BM, Debiec R, Nelson CP, Stark K, Tobin MD, Macfarlane PW,
Tomaszewski M, Samani NJ, Hengstenberg C. Heritability of early repolarization:
a population-based study. Circ Cardiovasc Genet. 2011 Apr;4(2):134-8. doi:
10.1161/CIRCGENETICS.110.958298. Epub 2011 Jan 31. PMID: 21282333.

Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss
M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H,
Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth
AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle
E, Braund PS, Brown MJ, Burnett MS, Buysschaert I; Cardiogenics, Carlquist JF,
Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney
JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R,
Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B,
Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen
SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA,
Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R,
Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci
PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O,
Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru
K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC,
Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal
FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert
A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M,
Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K,
Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G,
Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA,
Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T,
Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W,
Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR,
Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann
J; CARDIoGRAM Consortium, Samani NJ. Large-scale association analysis identifies
13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar
6;43(4):333-8. doi: 10.1038/ng.784. PMID: 21378990; PMCID: PMC3119261.

Kaess BM, Tomaszewski M, Braund PS, Stark K, Rafelt S, Fischer M, Hardwick
R, Nelson CP, Debiec R, Huber F, Kremer W, Kalbitzer HR, Rose LM, Chasman DI,
Hopewell J, Clarke R, Burton PR, Tobin MD, Hengstenberg C, Samani NJ. Large-
scale candidate gene analysis of HDL particle features. PLoS One. 2011 Jan
21;6(1):e14529. doi: 10.1371/journal.pone.0014529. PMID: 21283740; PMCID:
PMC3024972.

Baessler A, Schlossbauer S, Stark K, Strack C, Riegger G, Schunkert H,
Hengstenberg C, Fischer M. Adiponectin multimeric forms but not total
adiponectin levels are associated with myocardial infarction in non-diabetic
men. J Atheroscler Thromb. 2011;18(7):616-27. doi: 10.5551/jat.8359. Epub 2011
Apr 21. PMID: 21512277.

Erdmann J, Willenborg C, Nahrstaedt J, Preuss M, König IR, Baumert J,
Linsel-Nitschke P, Gieger C, Tennstedt S, Belcredi P, Aherrahrou Z, Klopp N,
Loley C, Stark K, Hengstenberg C, Bruse P, Freyer J, Wagner AK, Medack A, Lieb
W, Grosshennig A, Sager HB, Reinhardt A, Schäfer A, Schreiber S, El Mokhtari NE,
Raaz-Schrauder D, Illig T, Garlichs CD, Ekici AB, Reis A, Schrezenmeir J, Rubin
D, Ziegler A, Wichmann HE, Doering A, Meisinger C, Meitinger T, Peters A,
Schunkert H. Genome-wide association study identifies a new locus for coronary
artery disease on chromosome 10p11.23. Eur Heart J. 2011 Jan;32(2):158-68. doi:
10.1093/eurheartj/ehq405. Epub 2010 Nov 18. PMID: 21088011.

Kaess BM, Barnes TA, Stark K, Charchar FJ, Waterworth D, Song K, Wang WY,
Vollenweider P, Waeber G, Mooser V, Zukowska-Szczechowska E, Samani NJ,
Hengstenberg C, Tomaszewski M. FGF21 signalling pathway and metabolic traits -
genetic association analysis. Eur J Hum Genet. 2010 Dec;18(12):1344-8. doi:
10.1038/ejhg.2010.130. Epub 2010 Aug 18. PMID: 20717167; PMCID: PMC2988092.

Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF,
Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett MS,
Li M, Hlatky MA, Knowles JW, Thompson JR, Absher D, Iribarren C, Go A, Fortmann
SP, Sidney S, Risch N, Tang H, Myers RM, Berger K, Stoll M, Shah SH,
Thorgeirsson G, Andersen K, Havulinna AS, Herrera JE, Faraday N, Kim Y, Kral BG,
Mathias RA, Ruczinski I, Suktitipat B, Wilson AF, Yanek LR, Becker LC, Linsel-
Nitschke P, Lieb W, König IR, Hengstenberg C, Fischer M, Stark K, Reinhard W,
Winogradow J, Grassl M, Grosshennig A, Preuss M, Schreiber S, Wichmann HE,
Meisinger C, Yee J, Friedlander Y, Do R, Meigs JB, Williams G, Nathan DM, MacRae
CA, Qu L, Wilensky RL, Matthai WH Jr, Qasim AN, Hakonarson H, Pichard AD, Kent
KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser
VE, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Martinelli N, Olivieri O,
Trabetti E, Malerba G, Pignatti PF, Guiducci C, Mirel D, Parkin M, Hirschhorn
JN, Asselta R, Duga S, Musunuru K, Daly MJ, Purcell S, Eifert S, Braund PS,
Wright BJ, Balmforth AJ, Ball SG; Myocardial Infarction Genetics Consortium;
Wellcome Trust Case Control Consortium; Cardiogenics, Ouwehand WH, Deloukas P,
Scholz M, Cambien F, Huge A, Scheffold T, Salomaa V, Girelli D, Granger CB,
Peltonen L, McKeown PP, Altshuler D, Melander O, Devaney JM, Epstein SE, Rader
DJ, Elosua R, Engert JC, Anand SS, Hall AS, Ziegler A, O'Donnell CJ, Spertus JA,
Siscovick D, Schwartz SM, Becker D, Thorsteinsdottir U, Stefansson K, Schunkert
H, Samani NJ, Quertermous T. Lack of association between the Trp719Arg
polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-
control studies. J Am Coll Cardiol. 2010 Nov 2;56(19):1552-63. doi:
10.1016/j.jacc.2010.06.022. Erratum in: J Am Coll Cardiol. 2011 Jan
25;57(4):520. PMID: 20933357; PMCID: PMC3084526.

Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V,
Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC,
Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J,
Vedantam S, Esko T, Kilpeläinen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes
CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE,
Zondervan KT, Feitosa MF, Ferreira T, Lango Allen H, Weyant RJ, Wheeler E, Wood
AR; MAGIC, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S,
Smith AV, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin
N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ,
Johansson A, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P,
Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JR,
Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F,
Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V,
Zhao JH, Cavalcanti-Proença C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu
N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich TM, Timpson
NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J,
Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD,
Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day
IN, Dei M, Dörr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S,
Geus EJ, Gjesing AP, Grallert H, Grässler J, Groves CJ, Guiducci C, Hartikainen
AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P,
Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovacs P, Kroemer HK,
Krzelj V, Kuusisto J, Kvaloy K, Laitinen J, Lantieri O, Lathrop GM, Lokki ML,
Luben RN, Ludwig B, McArdle WL, McCarthy A, Morken MA, Nelis M, Neville MJ, Paré
G, Parker AN, Peden JF, Pichler I, Pietiläinen KH, Platou CG, Pouta A,
Ridderstråle M, Samani NJ, Saramies J, Sinisalo J, Smit JH, Strawbridge RJ,
Stringham HM, Swift AJ, Teder-Laving M, Thomson B, Usala G, van Meurs JB, van
Ommen GJ, Vatin V, Volpato CB, Wallaschofski H, Walters GB, Widen E, Wild SH,
Willemsen G, Witte DR, Zgaga L, Zitting P, Beilby JP, James AL, Kähönen M,
Lehtimäki T, Nieminen MS, Ohlsson C, Palmer LJ, Raitakari O, Ridker PM, Stumvoll
M, Tönjes A, Viikari J, Balkau B, Ben-Shlomo Y, Bergman RN, Boeing H, Smith GD,
Ebrahim S, Froguel P, Hansen T, Hengstenberg C, Hveem K, Isomaa B, Jørgensen T,
Karpe F, Khaw KT, Laakso M, Lawlor DA, Marre M, Meitinger T, Metspalu A,
Midthjell K, Pedersen O, Salomaa V, Schwarz PE, Tuomi T, Tuomilehto J, Valle TT,
Wareham NJ, Arnold AM, Beckmann JS, Bergmann S, Boerwinkle E, Boomsma DI,
Caulfield MJ, Collins FS, Eiriksdottir G, Gudnason V, Gyllensten U, Hamsten A,
Hattersley AT, Hofman A, Hu FB, Illig T, Iribarren C, Jarvelin MR, Kao WH,
Kaprio J, Launer LJ, Munroe PB, Oostra B, Penninx BW, Pramstaller PP, Psaty BM,
Quertermous T, Rissanen A, Rudan I, Shuldiner AR, Soranzo N, Spector TD, Syvanen
AC, Uda M, Uitterlinden A, Völzke H, Vollenweider P, Wilson JF, Witteman JC,
Wright AF, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, Frayling TM, Groop
LC, Haritunians T, Hunter DJ, Kaplan RC, North KE, O'Connell JR, Peltonen L,
Schlessinger D, Strachan DP, Hirschhorn JN, Assimes TL, Wichmann HE,
Thorsteinsdottir U, van Duijn CM, Stefansson K, Cupples LA, Loos RJ, Barroso I,
McCarthy MI, Fox CS, Mohlke KL, Lindgren CM. Meta-analysis identifies 13 new
loci associated with waist-hip ratio and reveals sexual dimorphism in the
genetic basis of fat distribution. Nat Genet. 2010 Nov;42(11):949-60. doi:
10.1038/ng.685. Epub 2010 Oct 10. Erratum in: Nat Genet. 2011 Nov;43(11):1164.
PMID: 20935629; PMCID: PMC3000924.

Stark K, Esslinger UB, Reinhard W, Petrov G, Winkler T, Komajda M, Isnard R,
Charron P, Villard E, Cambien F, Tiret L, Aumont MC, Dubourg O, Trochu JN,
Fauchier L, Degroote P, Richter A, Maisch B, Wichter T, Zollbrecht C, Grassl M,
Schunkert H, Linsel-Nitschke P, Erdmann J, Baumert J, Illig T, Klopp N, Wichmann
HE, Meisinger C, Koenig W, Lichtner P, Meitinger T, Schillert A, König IR,
Hetzer R, Heid IM, Regitz-Zagrosek V, Hengstenberg C. Genetic association study
identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy. PLoS
Genet. 2010 Oct 21;6(10):e1001167. doi: 10.1371/journal.pgen.1001167. PMID:
20975947; PMCID: PMC2958814.

Teupser D, Baber R, Ceglarek U, Scholz M, Illig T, Gieger C, Holdt LM,
Leichtle A, Greiser KH, Huster D, Linsel-Nitschke P, Schäfer A, Braund PS, Tiret
L, Stark K, Raaz-Schrauder D, Fiedler GM, Wilfert W, Beutner F, Gielen S,
Grosshennig A, König IR, Lichtner P, Heid IM, Kluttig A, El Mokhtari NE, Rubin
D, Ekici AB, Reis A, Garlichs CD, Hall AS, Matthes G, Wittekind C, Hengstenberg
C, Cambien F, Schreiber S, Werdan K, Meitinger T, Loeffler M, Samani NJ, Erdmann
J, Wichmann HE, Schunkert H, Thiery J. Genetic regulation of serum phytosterol
levels and risk of coronary artery disease. Circ Cardiovasc Genet. 2010
Aug;3(4):331-9. doi: 10.1161/CIRCGENETICS.109.907873. Epub 2010 Jun 7. PMID:
20529992.

Sinner MF, Reinhard W, Müller M, Beckmann BM, Martens E, Perz S, Pfeufer A,
Winogradow J, Stark K, Meisinger C, Wichmann HE, Peters A, Riegger GA, Steinbeck
G, Hengstenberg C, Kääb S. Association of early repolarization pattern on ECG
with risk of cardiac and all-cause mortality: a population-based prospective
cohort study (MONICA/KORA). PLoS Med. 2010 Jul 27;7(7):e1000314. doi:
10.1371/journal.pmed.1000314. PMID: 20668657; PMCID: PMC2910598.

Stark K, Straub RH, Blazicková S, Hengstenberg C, Rovenský J. Genetics in
neuroendocrine immunology: implications for rheumatoid arthritis and
osteoarthritis. Ann N Y Acad Sci. 2010 Apr;1193:10-4. doi:
10.1111/j.1749-6632.2009.05288.x. PMID: 20398001.

Denk AE, Kaufmann S, Stark K, Schedel J, Lowin T, Schubert T, Bosserhoff AK.
Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid
arthritis. Arthritis Res Ther. 2010;12(2):R45. doi: 10.1186/ar2955. Epub 2010
Mar 18. PMID: 20298552; PMCID: PMC2888193.

Linsel-Nitschke P, Heeren J, Aherrahrou Z, Bruse P, Gieger C, Illig T,
Prokisch H, Heim K, Doering A, Peters A, Meitinger T, Wichmann HE, Hinney A,
Reinehr T, Roth C, Ortlepp JR, Soufi M, Sattler AM, Schaefer J, Stark K,
Hengstenberg C, Schaefer A, Schreiber S, Kronenberg F, Samani NJ, Schunkert H,
Erdmann J. Genetic variation at chromosome 1p13.3 affects sortilin mRNA
expression, cellular LDL-uptake and serum LDL levels which translates to the
risk of coronary artery disease. Atherosclerosis. 2010 Jan;208(1):183-9. doi:
10.1016/j.atherosclerosis.2009.06.034. Epub 2009 Jul 8. PMID: 19660754.

Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka
T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J,
Florez JC, Langenberg C, Prokopenko I, Saxena R, Sladek R, Aulchenko Y, Evans D,
Waeber G, Erdmann J, Burnett MS, Sattar N, Devaney J, Willenborg C, Hingorani A,
Witteman JC, Vollenweider P, Glaser B, Hengstenberg C, Ferrucci L, Melzer D,
Stark K, Deanfield J, Winogradow J, Grassl M, Hall AS, Egan JM, Thompson JR,
Ricketts SL, König IR, Reinhard W, Grundy S, Wichmann HE, Barter P, Mahley R,
Kesaniemi YA, Rader DJ, Reilly MP, Epstein SE, Stewart AF, Van Duijn CM,
Schunkert H, Burling K, Deloukas P, Pastinen T, Samani NJ, McPherson R, Davey
Smith G, Frayling TM, Wareham NJ, Meigs JB, Mooser V, Spector TD; GIANT
Consortium. A genome-wide association study reveals variants in ARL15 that
influence adiponectin levels. PLoS Genet. 2009 Dec;5(12):e1000768. doi:
10.1371/journal.pgen.1000768. Epub 2009 Dec 11. PMID: 20011104; PMCID:
PMC2781107.

Stark K, Reinhard W, Grassl M, Erdmann J, Schunkert H, Illig T, Hengstenberg
C. Common polymorphisms influencing serum uric acid levels contribute to
susceptibility to gout, but not to coronary artery disease. PLoS One. 2009 Nov
5;4(11):e7729. doi: 10.1371/journal.pone.0007729. PMID: 19890391; PMCID:
PMC2766838.

Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg
C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y,
Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Döring A,
Elosua R, Epstein SE, Erber W, Falchi M, Garner SF, Ghori MJ, Goodall AH,
Gwilliam R, Hakonarson HH, Hall AS, Hammond N, Hengstenberg C, Illig T, König
IR, Knouff CW, McPherson R, Melander O, Mooser V, Nauck M, Nieminen MS,
O'Donnell CJ, Peltonen L, Potter SC, Prokisch H, Rader DJ, Rice CM, Roberts R,
Salomaa V, Sambrook J, Schreiber S, Schunkert H, Schwartz SM, Serbanovic-Canic
J, Sinisalo J, Siscovick DS, Stark K, Surakka I, Stephens J, Thompson JR, Völker
U, Völzke H, Watkins NA, Wells GA, Wichmann HE, Van Heel DA, Tyler-Smith C,
Thein SL, Kathiresan S, Perola M, Reilly MP, Stewart AF, Erdmann J, Samani NJ,
Meisinger C, Greinacher A, Deloukas P, Ouwehand WH, Gieger C. A genome-wide
meta-analysis identifies 22 loci associated with eight hematological parameters
in the HaemGen consortium. Nat Genet. 2009 Nov;41(11):1182-90. doi:
10.1038/ng.467. Epub 2009 Oct 11. PMID: 19820697; PMCID: PMC3108459.

Wiedmann S, Neureuther K, Stark K, Reinhard W, Kallmünzer B, Baessler A,
Fischer M, Linsel-Nitschke P, Erdmann J, Schunkert H, Hengstenberg C. Lack of
association between a common polymorphism near the INSIG2 gene and BMI,
myocardial infarction, and cardiovascular risk factors. Obesity (Silver Spring).
2009 Jul;17(7):1390-5. doi: 10.1038/oby.2008.669. Epub 2009 Feb 5. PMID:
19197259.

Erdmann J, Grosshennig A, Braund PS, König IR, Hengstenberg C, Hall AS,
Linsel-Nitschke P, Kathiresan S, Wright B, Trégouët DA, Cambien F, Bruse P,
Aherrahrou Z, Wagner AK, Stark K, Schwartz SM, Salomaa V, Elosua R, Melander O,
Voight BF, O'Donnell CJ, Peltonen L, Siscovick DS, Altshuler D, Merlini PA,
Peyvandi F, Bernardinelli L, Ardissino D, Schillert A, Blankenberg S, Zeller T,
Wild P, Schwarz DF, Tiret L, Perret C, Schreiber S, El Mokhtari NE, Schäfer A,
März W, Renner W, Bugert P, Klüter H, Schrezenmeir J, Rubin D, Ball SG,
Balmforth AJ, Wichmann HE, Meitinger T, Fischer M, Meisinger C, Baumert J,
Peters A, Ouwehand WH; Italian Atherosclerosis, Thrombosis, and Vascular Biology
Working Group; Myocardial Infarction Genetics Consortium; Wellcome Trust Case
Control Consortium; Cardiogenics Consortium, Deloukas P, Thompson JR, Ziegler A,
Samani NJ, Schunkert H. New susceptibility locus for coronary artery disease on
chromosome 3q22.3. Nat Genet. 2009 Mar;41(3):280-2. doi: 10.1038/ng.307. Epub
2009 Feb 8. PMID: 19198612; PMCID: PMC2695543.

Trégouët DA, König IR, Erdmann J, Munteanu A, Braund PS, Hall AS,
Grosshennig A, Linsel-Nitschke P, Perret C, DeSuremain M, Meitinger T, Wright
BJ, Preuss M, Balmforth AJ, Ball SG, Meisinger C, Germain C, Evans A, Arveiler
D, Luc G, Ruidavets JB, Morrison C, van der Harst P, Schreiber S, Neureuther K,
Schäfer A, Bugert P, El Mokhtari NE, Schrezenmeir J, Stark K, Rubin D, Wichmann
HE, Hengstenberg C, Ouwehand W; Wellcome Trust Case Control Consortium;
Cardiogenics Consortium, Ziegler A, Tiret L, Thompson JR, Cambien F, Schunkert
H, Samani NJ. Genome-wide haplotype association study identifies the
SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat
Genet. 2009 Mar;41(3):283-5. doi: 10.1038/ng.314. Epub 2009 Feb 8. PMID:
19198611.

Myocardial Infarction Genetics Consortium, Kathiresan S, Voight BF, Purcell
S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ,
Schunkert H, Erdmann J, Reilly MP, Rader DJ, Morgan T, Spertus JA, Stoll M,
Girelli D, McKeown PP, Patterson CC, Siscovick DS, O'Donnell CJ, Elosua R,
Peltonen L, Salomaa V, Schwartz SM, Melander O, Altshuler D, Ardissino D,
Merlini PA, Berzuini C, Bernardinelli L, Peyvandi F, Tubaro M, Celli P, Ferrario
M, Fetiveau R, Marziliano N, Casari G, Galli M, Ribichini F, Rossi M, Bernardi
F, Zonzin P, Piazza A, Mannucci PM, Schwartz SM, Siscovick DS, Yee J,
Friedlander Y, Elosua R, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R,
Kathiresan S, Meigs JB, Williams G, Nathan DM, MacRae CA, O'Donnell CJ, Salomaa
V, Havulinna AS, Peltonen L, Melander O, Berglund G, Voight BF, Kathiresan S,
Hirschhorn JN, Asselta R, Duga S, Spreafico M, Musunuru K, Daly MJ, Purcell S,
Voight BF, Purcell S, Nemesh J, Korn JM, McCarroll SA, Schwartz SM, Yee J,
Kathiresan S, Lucas G, Subirana I, Elosua R, Surti A, Guiducci C, Gianniny L,
Mirel D, Parkin M, Burtt N, Gabriel SB, Samani NJ, Thompson JR, Braund PS,
Wright BJ, Balmforth AJ, Ball SG, Hall A; Wellcome Trust Case Control
Consortium, Schunkert H, Erdmann J, Linsel-Nitschke P, Lieb W, Ziegler A, König
I, Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE,
Schreiber S, Schunkert H, Samani NJ, Erdmann J, Ouwehand W, Hengstenberg C,
Deloukas P, Scholz M, Cambien F, Reilly MP, Li M, Chen Z, Wilensky R, Matthai W,
Qasim A, Hakonarson HH, Devaney J, Burnett MS, Pichard AD, Kent KM, Satler L,
Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser V, Epstein
SE, Rader DJ, Scheffold T, Berger K, Stoll M, Huge A, Girelli D, Martinelli N,
Olivieri O, Corrocher R, Morgan T, Spertus JA, McKeown P, Patterson CC,
Schunkert H, Erdmann E, Linsel-Nitschke P, Lieb W, Ziegler A, König IR,
Hengstenberg C, Fischer M, Stark K, Grosshennig A, Preuss M, Wichmann HE,
Schreiber S, Hólm H, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Engert
JC, Do R, Xie C, Anand S, Kathiresan S, Ardissino D, Mannucci PM, Siscovick D,
O'Donnell CJ, Samani NJ, Melander O, Elosua R, Peltonen L, Salomaa V, Schwartz
SM, Altshuler D. Genome-wide association of early-onset myocardial infarction
with single nucleotide polymorphisms and copy number variants. Nat Genet. 2009
Mar;41(3):334-41. doi: 10.1038/ng.327. Epub 2009 Feb 8. Erratum in: Nat Genet.
2009 Jun;41(6):762. Knouff, Christopher W [added]; Waterworth, Dawn M [added];
Walker, Max C [added]; Mooser, Vincent [added]. PMID: 19198609; PMCID:
PMC2681011.

Stark K, Rovenský J, Blazicková S, Grosse-Wilde H, Ferencik S, Hengstenberg
C, Straub RH. Association of common polymorphisms in known susceptibility genes
with rheumatoid arthritis in a Slovak population using osteoarthritis patients
as controls. Arthritis Res Ther. 2009;11(3):R70. doi: 10.1186/ar2699. Epub 2009
May 15. PMID: 19445664; PMCID: PMC2714116.

Sedlacek K, Stark K, Cunha SR, Pfeufer A, Weber S, Berger I, Perz S, Kääb S,
Wichmann HE, Mohler PJ, Hengstenberg C, Jeron A. Common genetic variants in ANK2
modulate QT interval: results from the KORA study. Circ Cardiovasc Genet. 2008
Dec;1(2):93-9. doi: 10.1161/CIRCGENETICS.108.792192. Epub 2008 Dec 9. PMID:
20031550.

Samani NJ, Braund PS, Erdmann J, Götz A, Tomaszewski M, Linsel-Nitschke P,
Hajat C, Mangino M, Hengstenberg C, Stark K, Ziegler A, Caulfield M, Burton PR,
Schunkert H, Tobin MD. The novel genetic variant predisposing to coronary artery
disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates
with serum cholesterol. J Mol Med (Berl). 2008 Nov;86(11):1233-41. doi:
10.1007/s00109-008-0387-2. Epub 2008 Jul 23. PMID: 18649068.

Reinhard W, Stark K, Sedlacek K, Fischer M, Baessler A, Neureuther K, Weber
S, Kaess B, Wiedmann S, Mitsching S, Lieb W, Erdmann J, Meisinger C, Doering A,
Tolle R, Jeron A, Riegger G, Hengstenberg C. Association between PPARalpha gene
polymorphisms and myocardial infarction. Clin Sci (Lond). 2008
Nov;115(10):301-8. doi: 10.1042/CS20070391. PMID: 18336366.

Linsel-Nitschke P, Götz A, Medack A, König IR, Bruse P, Lieb W, Mayer B,
Stark K, Hengstenberg C, Fischer M, Baessler A, Ziegler A, Schunkert H, Erdmann
J. Genetic variation in the arachidonate 5-lipoxygenase-activating protein
(ALOX5AP) is associated with myocardial infarction in the German population.
Clin Sci (Lond). 2008 Nov;115(10):309-15. doi: 10.1042/CS20070468. PMID:
18318662.

Lieb W, Zeller T, Mangino M, Götz A, Braund P, Wenzel JJ, Horn C, Proust C,
Linsel-Nitschke P, Amouyel P, Bruse P, Arveiler D, König IR, Ferrières J,
Ziegler A, Balmforth AJ, Evans A, Ducimetière P, Cambien F, Hengstenberg C,
Stark K, Hall AS, Schunkert H, Blankenberg S, Samani NJ, Erdmann J, Tiret L.
Lack of association of genetic variants in the LRP8 gene with familial and
sporadic myocardial infarction. J Mol Med (Berl). 2008 Oct;86(10):1163-70. doi:
10.1007/s00109-008-0376-5. Epub 2008 Jul 1. PMID: 18592168.

Linsel-Nitschke P, Götz A, Erdmann J, Braenne I, Braund P, Hengstenberg C,
Stark K, Fischer M, Schreiber S, El Mokhtari NE, Schaefer A, Schrezenmeir J,
Rubin D, Hinney A, Reinehr T, Roth C, Ortlepp J, Hanrath P, Hall AS, Mangino M,
Lieb W, Lamina C, Heid IM, Doering A, Gieger C, Peters A, Meitinger T, Wichmann
HE, König IR, Ziegler A, Kronenberg F, Samani NJ, Schunkert H; Wellcome Trust
Case Control Consortium (WTCCC); Cardiogenics Consortium. Lifelong reduction of
LDL-cholesterol related to a common variant in the LDL-receptor gene decreases
the risk of coronary artery disease--a Mendelian Randomisation study. PLoS One.
2008 Aug 20;3(8):e2986. doi: 10.1371/journal.pone.0002986. Erratum in: PLoS ONE.
2008;3(9). doi: 10.1371/annotation/9f64c41a-8cf6-40f2-8988-0d48b04dd8cb.
Schrezenmeier, Jürgen [corrected to Schrezenmeir, Jürgen]. PMID: 18714375;
PMCID: PMC2500189.

Reinhard W, Stark K, Neureuther K, Sedlacek K, Fischer M, Baessler A, Weber
S, Kaess B, Wiedmann S, Erdmann J, Lieb W, Jeron A, Riegger G, Hengstenberg C.
Common polymorphisms in the cannabinoid CB2 receptor gene (CNR2) are not
associated with myocardial infarction and cardiovascular risk factors. Int J Mol
Med. 2008 Aug;22(2):165-74. PMID: 18636169.

Stark K, Reinhard W, Neureuther K, Wiedmann S, Sedlacek K, Baessler A,
Fischer M, Weber S, Kaess B, Erdmann J, Schunkert H, Hengstenberg C. Association
of common polymorphisms in GLUT9 gene with gout but not with coronary artery
disease in a large case-control study. PLoS One. 2008 Apr 9;3(4):e1948. doi:
10.1371/journal.pone.0001948. PMID: 18398472; PMCID: PMC2275796.

Schunkert H, Götz A, Braund P, McGinnis R, Tregouet DA, Mangino M, Linsel-
Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L,
Ducimetiere P, Keniry A, Ghori MJ, Schreiber S, El Mokhtari NE, Hall AS, Dixon
RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann HE, König
IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J,
Ziegler A, Samani NJ; Cardiogenics Consortium. Repeated replication and a
prospective meta-analysis of the association between chromosome 9p21.3 and
coronary artery disease. Circulation. 2008 Apr 1;117(13):1675-84. doi:
10.1161/CIRCULATIONAHA.107.730614. Epub 2008 Mar 24. PMID: 18362232; PMCID:
PMC2689930.

Kaess B, Fischer M, Baessler A, Stark K, Huber F, Kremer W, Kalbitzer HR,
Schunkert H, Riegger G, Hengstenberg C. The lipoprotein subfraction profile:
heritability and identification of quantitative trait loci. J Lipid Res. 2008
Apr;49(4):715-23. doi: 10.1194/jlr.M700338-JLR200. Epub 2007 Dec 28. PMID:
18165655.

Sedlacek K, Neureuther K, Mueller JC, Stark K, Fischer M, Baessler A,
Reinhard W, Broeckel U, Lieb W, Erdmann J, Schunkert H, Riegger G, Illig T,
Meitinger T, Hengstenberg C. Lymphotoxin-alpha and galectin-2 SNPs are not
associated with myocardial infarction in two different German populations. J Mol
Med (Berl). 2007 Sep;85(9):997-1004. doi: 10.1007/s00109-007-0211-4. Epub 2007
May 12. PMID: 17497114.

Stark K, Neureuther K, Sedlacek K, Hengstenberg W, Fischer M, Baessler A,
Wiedmann S, Jeron A, Holmer S, Erdmann J, Schunkert H, Hengstenberg C. The
common Y402H variant in complement factor H gene is not associated with
susceptibility to myocardial infarction and its related risk factors. Clin Sci
(Lond). 2007 Aug;113(4):213-8. doi: 10.1042/CS20070028. PMID: 17472578.

Baessler A, Fischer M, Mayer B, Koehler M, Wiedmann S, Stark K, Doering A,
Erdmann J, Riegger G, Schunkert H, Kwitek AE, Hengstenberg C. Epistatic
interaction between haplotypes of the ghrelin ligand and receptor genes
influence susceptibility to myocardial infarction and coronary artery disease.
Hum Mol Genet. 2007 Apr 15;16(8):887-99. doi: 10.1093/hmg/ddm033. Epub 2007 Feb
26. PMID: 17324965.

Baessler A, Fischer M, Hubauer U, Stark K, Hengstenberg W, Wiedmann S,
Neureuther K, Holmer S, Mayer B, Schunkert H, Hengstenberg C. Nach dem ersten
Myokardinfarkt. Je schlechter die Lipidtherapie, desto schlechter die Prognose
[Prognostic implictions of the lack of a lipid-lowering strategy]. MMW Fortschr
Med. 2006 Nov 2;148(44):38. German. PMID: 17619439.

Jakobiak T, Mages W, Scharf B, Babinger P, Stark K, Schmitt R. The bacterial
paromomycin resistance gene, aphH, as a dominant selectable marker in Volvox
carteri. Protist. 2004 Dec;155(4):381-93. doi: 10.1078/1434461042650343. PMID:
15648719.

Stark K, Schmitt R. Genetic control of germ-soma differentiation in Volvox
carteri. Protist. 2002 Jun;153(2):99-107. doi: 10.1078/1434-4610-00088. PMID:
12125761.

Stark K, Kirk DL, Schmitt R. Two enhancers and one silencer located in the
introns of regA control somatic cell differentiation in Volvox carteri. Genes
Dev. 2001 Jun 1;15(11):1449-60. doi: 10.1101/gad.195101. PMID: 11390364; PMCID:
PMC312706.

Meissner M, Stark K, Cresnar B, Kirk DL, Schmitt R. Volvox germline-specific
genes that are putative targets of RegA repression encode chloroplast proteins.
Curr Genet. 1999 Dec;36(6):363-70. doi: 10.1007/s002940050511. PMID: 10654090.

Kirk MM, Stark K, Miller SM, Müller W, Taillon BE, Gruber H, Schmitt R, Kirk
DL. regA, a Volvox gene that plays a central role in germ-soma differentiation,
encodes a novel regulatory protein. Development. 1999 Feb;126(4):639-47. doi:
10.1242/dev.126.4.639. PMID: 9895312.



  1. Fakultät für Medizin

Prof. Dr. Klaus Stark

Lehrstuhl für Genetische Epidemiologie

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