Prof. Dr. Günther Bernhardt (im Ruhestand)

Prof. Dr. Günther Bernhardt

E-Mail guenther.bernhardt@ur.de

Forschungsschwerpunkte:

• Biochemical / pharmacological exploration of neuropeptide Y / histamine receptor ligands and of potential anti-cancer agents
• Development and application of luminescence-based methods for the determination of the affinity and activity of GPCR ligands
• In vivo imaging (fluorescence, bioluminescence, PET)
• Analytical and biopharmaceutical investigations (HPLC, CE, AAS)
• Heterologous expression, renaturation, purification and enzymological characterization of human hyaluronidases
• Investigation of the effect of hyaluronidase and hyaluronan synthetase on tumorigenicity, growth and metastasis of human malignant tumors in nude mice
• Preclinical (in vitro / in vivo) studies on the treatment of primary and secondary brain tumors
• Preclinical investigations on hormone sensitive malignancies (especially mammary carcinoma, cancer of the prostate)

Zusätzliche Forschungsinteressen:

• Medical occultism